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Immunomodulatory effects of the tobacco-specific carcinogen, NNK, on alveolar macrophages

Lung cancer is strongly associated with cigarette smoking. More than 20 lung carcinogens have been identified in cigarette smoke and one of the most abundant is 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). We hypothesized that NNK modulates alveolar macrophage (AM) mediator production, thus...

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Detalhes bibliográficos
Main Authors: THERRIAULT, M-J, PROULX, L-I, CASTONGUAY, A, BISSONNETTE, É Y
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808690/
https://ncbi.nlm.nih.gov/pubmed/12699410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02142.x
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