High circulating levels of biologically inactive IL-6/SIL-6 receptor complexes in systemic juvenile idiopathic arthritis: evidence for serum factors interfering with the binding to gp130

We previously demonstrated that high levels of IL-6/sIL-6R complexes are present in sera of patients with systemic juvenile idiopathic arthritis (s-JIA) and that the amount of IL-6 estimated in the IL-6/sIL-6R complexes is markedly higher than that measured by the B9 assay. Here, we show that two ad...

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Detalhes bibliográficos
Main Authors: PIGNATTI, P, CIAPPONI, L, GALLE, P, HANSEN, M B, MASSA, M, MEAZZA, C, PAONESSA, G, NOVICK, D, CILIBERTO, G, MARTINI, A, DE BENEDETTI, F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2003
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808632/
https://ncbi.nlm.nih.gov/pubmed/12562400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02052.x
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