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FMRP Mediates mGluR(5)-Dependent Translation of Amyloid Precursor Protein
Amyloid precursor protein (APP) facilitates synapse formation in the developing brain, while beta-amyloid (Aβ) accumulation, which is associated with Alzheimer disease, results in synaptic loss and impaired neurotransmission. Fragile X mental retardation protein (FMRP) is a cytoplasmic mRNA binding...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Public Library of Science
2007
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1808499/ https://ncbi.nlm.nih.gov/pubmed/17298186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050052 |
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