Precancerous Stem Cells Have the Potential for both Benign and Malignant Differentiation

Cancer stem cells (CSCs) have been identified in hematopoietic and solid tumors. However, their precursors—namely, precancerous stem cells (pCSCs) —have not been characterized. Here we experimentally define the pCSCs that have the potential for both benign and malignant differentiation, depending on...

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Autori principali: Chen, Li, Shen, Rulong, Ye, Yin, Pu, Xin-An, Liu, Xingluo, Duan, Wenrui, Wen, Jing, Zimmerer, Jason, Wang, Ying, Liu, Yan, Lasky, Larry C., Heerema, Nyla A., Perrotti, Danilo, Ozato, Keiko, Kuramochi-Miyagawa, Satomi, Nakano, Toru, Yates, Allen J., Carson III, William E., Lin, Haifan, Barsky, Sanford H., Gao, Jian-Xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808425/
https://ncbi.nlm.nih.gov/pubmed/17356702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000293
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