Gene-specific recruitment of positive and negative elongation factors during stimulated transcription of the MKP-1 gene in neuroendocrine cells

MAP kinase phosphatase-1 (MKP-1) controls nuclear MAP kinase activity with important consequences on cell growth or apoptosis. MKP-1 transcription is initiated constitutively but elongation is blocked within exon 1. It is unclear how induction of MKP-1 is controlled. Here, we report that the transcr...

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Bibliographische Detailangaben
Hauptverfasser: Fujita, Toshitsugu, Ryser, Stephan, Tortola, Silvia, Piuz, Isabelle, Schlegel, Werner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2007
Schlagworte:
Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807974/
https://ncbi.nlm.nih.gov/pubmed/17259211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1138
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