Bacterial protein HU dictates the morphology of DNA condensates produced by crowding agents and polyamines

Controlling the size and shape of DNA condensates is important in vivo and for the improvement of nonviral gene delivery. Here, we demonstrate that the morphology of DNA condensates, formed under a variety of conditions, is shifted completely from toroids to rods if the bacterial protein HU is prese...

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Bibliographic Details
Main Authors: Sarkar, Tumpa, Vitoc, Iulia, Mukerji, Ishita, Hud, Nicholas V.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807954/
https://ncbi.nlm.nih.gov/pubmed/17259223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1093
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