Troglitazone prevents mitochondrial alterations, β cell destruction, and diabetes in obese prediabetic rats

To determine whether the antidiabetic action of troglitazone (TGZ), heretofore attributed to insulin sensitization, also involves protection of β cells from lipoapoptosis, we treated prediabetic Zucker Diabetic Fatty rats with 200 mg/kg per day of TGZ. Their plasma-free fatty acids and triacylglycer...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Higa, Moritake, Zhou, Yan-Ting, Ravazzola, Mariella, Baetens, Danielle, Orci, Lelio, Unger, Roger H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC18065/
https://ncbi.nlm.nih.gov/pubmed/10500208
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk