The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene

The goal of this study was to interrogate the role of inducible NO synthase (iNOS) in the late phase of ischemic preconditioning (PC) in vivo. A total of 321 mice were used. Wild-type mice preconditioned 24 h earlier with six cycles of 4-min coronary occlusion/4-min reperfusion exhibited a significa...

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Main Authors: Guo, Yiru, Jones, W. Keith, Xuan, Yu-Ting, Tang, Xian-Liang, Bao, Weike, Wu, Wen-Jian, Han, Hui, Laubach, Victor E., Ping, Peipei, Yang, Zequan, Qiu, Yumin, Bolli, Roberto
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC18064/
https://ncbi.nlm.nih.gov/pubmed/10500207
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