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MHC class II antigen loading compartments continuously receive input from autophagosomes

Major histocompatibility complex (MHC) class II molecules present products of lysosomal proteolysis to CD4(+) T cells. While extracellular antigen uptake is considered to be the main source of MHC class II-ligands, a few intracellular antigens have been described to gain access to MHC class II loadi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schmid, Dorothee, Pypaert, Marc, Münz, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805710/
https://ncbi.nlm.nih.gov/pubmed/17182262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2006.10.018
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