Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells
The identity of cells that mediate positive selection of CD8(+) T cells was investigated in two T cell receptor (TCR) transgenic systems. Irradiated β(2)-microglobulin mutant mice or mice with mutations in both the K(b) and D(b) genes were repopulated with fetal liver cells from class I(+) TCR trans...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1999
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11470 |
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