RmlC, a C3′ and C3′ carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation.

The striking feature of carbohydrates is their constitutional, conformational and configurational diversity. Biology has harnessed this diversity and manipulates carbohydrate residues in a variety of ways, one of which is epimerization. RmlC catalyzes the epimerization of the C3′ and C5′ positions o...

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Main Authors: Dong, Changjiang, Major, Louise L., Srikannathasan, Velupillai, Errey, James C., Giraud, Marie-France, Lam, Joseph S., Graninger, Michael, Messner, Paul, McNeil, Michael R., Field, Robert A., Whitfield, Chris, Naismith, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805628/
https://ncbi.nlm.nih.gov/pubmed/17046787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.063
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