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Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization
Polo-like kinase (Plk1) is crucial for cell cycle progression through mitosis. Here we present the molecular and structural mechanisms that regulate the substrate recognition of Plk1 and influence its centrosomal localization and activity. Our work shows that Plk1 localization is controlled not only...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1805623/ https://ncbi.nlm.nih.gov/pubmed/17307877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609131104 |
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