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Quantifying DNA–protein binding specificities by using oligonucleotide mass tags and mass spectroscopy

The ability to determine the relative binding affinity of different transcription-factors (TF) to their DNA binding sites is fundamentally important for a comprehensive understanding of gene regulation. Here we present a general approach for multiplex quantification of DNA-TF binding specificities i...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Lingang, Kasif, Simon, Cantor, and Charles R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805538/
https://ncbi.nlm.nih.gov/pubmed/17360609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611075104
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