Invariant NKT cells sustain specific B cell responses and memory

Invariant natural killer T (iNKT) cells are innate-like lymphocytes recognizing CD1d-restricted glycolipid antigens, such as α-galactosylceramide (αGC). We assessed whether iNKT cells help B lymphocyte responses and found that mice immunized with proteins and αGC develop antibody titers 1–2 logs hig...

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Hauptverfasser: Galli, Grazia, Pittoni, Paola, Tonti, Elena, Malzone, Carmine, Uematsu, Yasushi, Tortoli, Marco, Maione, Domenico, Volpini, Gianfranco, Finco, Oretta, Nuti, Sandra, Tavarini, Simona, Dellabona, Paolo, Rappuoli, Rino, Casorati, Giulia, Abrignani, Sergio
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805488/
https://ncbi.nlm.nih.gov/pubmed/17360464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700191104
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