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Progranulin in frontotemporal lobar degeneration and neuroinflammation

Progranulin (PGRN) is a pleiotropic protein that has gained the attention of the neuroscience community with recent discoveries of mutations in the gene for PGRN that cause frontotemporal lobar degeneration (FTLD). Pathogenic mutations in PGRN result in null alleles, and the disease is likely the re...

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Autori principali: Ahmed, Zeshan, Mackenzie, Ian RA, Hutton, Michael L, Dickson, Dennis W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805428/
https://ncbi.nlm.nih.gov/pubmed/17291356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-7
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