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Progranulin in frontotemporal lobar degeneration and neuroinflammation

Progranulin (PGRN) is a pleiotropic protein that has gained the attention of the neuroscience community with recent discoveries of mutations in the gene for PGRN that cause frontotemporal lobar degeneration (FTLD). Pathogenic mutations in PGRN result in null alleles, and the disease is likely the re...

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Detalhes bibliográficos
Main Authors: Ahmed, Zeshan, Mackenzie, Ian RA, Hutton, Michael L, Dickson, Dennis W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805428/
https://ncbi.nlm.nih.gov/pubmed/17291356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-7
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