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Loss of Vav2 Proto-Oncogene Causes Tachycardia and Cardiovascular Disease in Mice

The Vav family is a group of signal transduction molecules that activate Rho/Rac GTPases during cell signaling. Experiments using knockout mice have indicated that the three Vav proteins present in mammals (Vav1, Vav2, and Vav3) are essential for proper signaling responses in hematopoietic cells. Ho...

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Bibliografski detalji
Glavni autori: Sauzeau, Vincent, Jerkic, Mirjana, López-Novoa, José M., Bustelo, Xosé R.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805112/
https://ncbi.nlm.nih.gov/pubmed/17202406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0877
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