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Loss of Vav2 Proto-Oncogene Causes Tachycardia and Cardiovascular Disease in Mice
The Vav family is a group of signal transduction molecules that activate Rho/Rac GTPases during cell signaling. Experiments using knockout mice have indicated that the three Vav proteins present in mammals (Vav1, Vav2, and Vav3) are essential for proper signaling responses in hematopoietic cells. Ho...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1805112/ https://ncbi.nlm.nih.gov/pubmed/17202406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0877 |
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