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Disposition of carumonam (AMA-1080/Ro 17-2301), a new N-sulfonated monocyclic beta-lactam, in rats and dogs.

Rats and dogs were given a single 20-mg/kg dose of [14C]carumonam intramuscularly or intravenously. In rats, the level in plasma of [14C]carumonam administered intramuscularly peaked (29.1 micrograms/ml) 15 min after dosing and then declined with an apparent elimination half-life of 16.2 min. Intram...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Antimicrob Agents Chemother
Príomhchruthaitheoirí: Yoshida, K, Mitani, M, Naeshiro, I, Torii, H, Tanayama, S
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 1986
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180494/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3729358/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.6.1017
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