Disposition of carumonam (AMA-1080/Ro 17-2301), a new N-sulfonated monocyclic beta-lactam, in rats and dogs.

Rats and dogs were given a single 20-mg/kg dose of [14C]carumonam intramuscularly or intravenously. In rats, the level in plasma of [14C]carumonam administered intramuscularly peaked (29.1 micrograms/ml) 15 min after dosing and then declined with an apparent elimination half-life of 16.2 min. Intram...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Yoshida, K, Mitani, M, Naeshiro, I, Torii, H, Tanayama, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180494/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3729358/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.6.1017
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!