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Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres

Fission yeast shugoshin Sgo1 is meiosis specific and cooperates with protein phosphatase 2A to protect centromeric cohesin at meiosis I. The other shugoshin-like protein Sgo2, which requires the heterochromatin protein Swi6/HP1 for full viability, plays a crucial role for proper chromosome segregati...

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Bibliographic Details
Main Authors: Kawashima, Shigehiro A., Tsukahara, Tatsuya, Langegger, Maria, Hauf, Silke, Kitajima, Tomoya S., Watanabe, Yoshinori
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1804331/
https://ncbi.nlm.nih.gov/pubmed/17322402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1497307
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