Single-dose pharmacokinetics of 3-O-demethylfortimicin A in humans after intravenous and intramuscular administration.

The pharmacokinetics of 3-O-demethylfortimicin A were evaluated in 16 healthy adult male volunteers after bolus intramuscular (i.m.) and 30-min intravenous (i.v.) infusion administration of doses ranging from 0.25 to 16 mg/kg. Mean calculated peak levels of the drug in plasma after the 0.25-, 0.5-,...

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Bibliografiska uppgifter
Huvudupphovsmän: Sennello, L T, Wilson, D S, Afarian, J, Holtam, L S, Norman, G, Rollins, D E, Tolman, K G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1986
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC180402/
https://ncbi.nlm.nih.gov/pubmed/3717941
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