Single-dose pharmacokinetics of 3-O-demethylfortimicin A in humans after intravenous and intramuscular administration.

The pharmacokinetics of 3-O-demethylfortimicin A were evaluated in 16 healthy adult male volunteers after bolus intramuscular (i.m.) and 30-min intravenous (i.v.) infusion administration of doses ranging from 0.25 to 16 mg/kg. Mean calculated peak levels of the drug in plasma after the 0.25-, 0.5-,...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Sennello, L T, Wilson, D S, Afarian, J, Holtam, L S, Norman, G, Rollins, D E, Tolman, K G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180402/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3717941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.3.400
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