RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

A RING finger-containing protein (AO7) that binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination was identified. Mutations of cation-coordinating residues within AO7’s RING finger abolished ubiquitination, as did chelation of zinc. Several otherwise-unrelated...

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Bibliografske podrobnosti
Main Authors: Lorick, Kevin L., Jensen, Jane P., Fang, Shengyun, Ong, Albert M., Hatakeyama, Shigetsugu, Weissman, Allan M.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC18039/
https://ncbi.nlm.nih.gov/pubmed/10500182
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