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Synthesis and antibacterial activities of optically active ofloxacin.

Two optically active (100% enantiomeric excess) isomers of ofloxacin [(+/-)-ofloxacin; DL-8280; (+/-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7 H-pyrido[1,2,3-de] [1,4] benzoxazine-6-carboxylic acid] were prepared by use of their optically resolved synthetic intermediates. On...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Hayakawa, I, Atarashi, S, Yokohama, S, Imamura, M, Sakano, K, Furukawa, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180386/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3460520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.1.163
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