Synthesis and antibacterial activities of optically active ofloxacin.

Two optically active (100% enantiomeric excess) isomers of ofloxacin [(+/-)-ofloxacin; DL-8280; (+/-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7 H-pyrido[1,2,3-de] [1,4] benzoxazine-6-carboxylic acid] were prepared by use of their optically resolved synthetic intermediates. On...

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Bibliografiske detaljer
Main Authors: Hayakawa, I, Atarashi, S, Yokohama, S, Imamura, M, Sakano, K, Furukawa, M
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC180386/
https://ncbi.nlm.nih.gov/pubmed/3460520
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