Conversion of 5-fluorocytosine to 5-fluorouracil by human intestinal microflora.
The mechanism of toxicity from 5-fluorocytosine chemotherapy is unclear. However, recent evidence suggests that the generation of 5-fluorouracil by a host may play an important role in the development of this toxicity. Using an in vitro semicontinuous culture system to mimic the intestinal microflor...
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| 發表在: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
1986
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3729334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.1.44 |
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