Conversion of 5-fluorocytosine to 5-fluorouracil by human intestinal microflora.

The mechanism of toxicity from 5-fluorocytosine chemotherapy is unclear. However, recent evidence suggests that the generation of 5-fluorouracil by a host may play an important role in the development of this toxicity. Using an in vitro semicontinuous culture system to mimic the intestinal microflor...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Harris, B E, Manning, B W, Federle, T W, Diasio, R B
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1986
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3729334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.1.44
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