Hydrophobic polyoxins are resistant to intracellular degradation in Candida albicans.

Two novel polyoxins, N-epsilon-(octanoyl)-lysyl-uracil polyoxin C (Oct-Lys-UPOC) and N-gamma-(octyl)-glutaminyluracil polyoxin C (Oct-Gln-UPOC), were synthesized by reacting uracil polyoxin C with the appropriate amino acid p-nitrophenyl ester. Oct-Lys-UPOC and Oct-Gln-UPOC were strong inhibitors (K...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Smith, H A, Shenbagamurthi, P, Naider, F, Kundu, B, Becker, J M
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1986
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3524423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.1.33
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