Hydrophobic polyoxins are resistant to intracellular degradation in Candida albicans.
Two novel polyoxins, N-epsilon-(octanoyl)-lysyl-uracil polyoxin C (Oct-Lys-UPOC) and N-gamma-(octyl)-glutaminyluracil polyoxin C (Oct-Gln-UPOC), were synthesized by reacting uracil polyoxin C with the appropriate amino acid p-nitrophenyl ester. Oct-Lys-UPOC and Oct-Gln-UPOC were strong inhibitors (K...
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| 發表在: | Antimicrob Agents Chemother |
|---|---|
| Principais autores: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
1986
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3524423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.1.33 |
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