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Effect of pyrimidinone treatment on lethal and immunosuppressive murine cytomegalovirus infection.

The 2-amino-5-halo-pyrimidinones, which are potent interferon inducers and antiviral agents, were found to be protective against lethal cytomegalovirus (CMV) challenge in weanling or neonatal mice when administered before virus challenge. This protection was dependent upon the dosage of pyrimidinone...

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Autors principals: Brideau, R J, Wolcott, J A
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC180288/
https://ncbi.nlm.nih.gov/pubmed/3000290
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