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Effect of pyrimidinone treatment on lethal and immunosuppressive murine cytomegalovirus infection.

The 2-amino-5-halo-pyrimidinones, which are potent interferon inducers and antiviral agents, were found to be protective against lethal cytomegalovirus (CMV) challenge in weanling or neonatal mice when administered before virus challenge. This protection was dependent upon the dosage of pyrimidinone...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Brideau, R J, Wolcott, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3000290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.4.485
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