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Influence of four modes of administration on penetration of aztreonam, cefuroxime, and ampicillin into interstitial fluid and fibrin clots and on in vivo efficacy against Haemophilus influenzae.

The extravascular penetration and bactericidal activity of aztreonam, cefuroxime, and ampicillin against beta-lactamase-positive and -negative Haemophilus influenzae strains were compared in a rabbit model. All groups of animals received an identical total dose of 100 mg of either antibiotic per kg...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Lavoie, G Y, Bergeron, M G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180262/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3878128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.3.404
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