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Influence of four modes of administration on penetration of aztreonam, cefuroxime, and ampicillin into interstitial fluid and fibrin clots and on in vivo efficacy against Haemophilus influenzae.

The extravascular penetration and bactericidal activity of aztreonam, cefuroxime, and ampicillin against beta-lactamase-positive and -negative Haemophilus influenzae strains were compared in a rabbit model. All groups of animals received an identical total dose of 100 mg of either antibiotic per kg...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Lavoie, G Y, Bergeron, M G
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1985
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180262/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3878128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.3.404
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