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Expression of human pim family genes is selectively up-regulated by cytokines promoting T helper type 1, but not T helper type 2, cell differentiation

Cytokines are the most important inducers of T helper (Th) cell differentiation. Interleukin-12 (IL-12) and interferon-α (IFN-α) are responsible for human Th1-cell differentiation, while IL-4 is the critical cytokine promoting Th2-cell development. These two subsets of cells co-ordinate immunologica...

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Detalhes bibliográficos
Main Authors: Aho, Teija L T, Lund, Riikka J, Ylikoski, Emmi K, Matikainen, Sampsa, Lahesmaa, Riitta, Koskinen, Päivi J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802411/
https://ncbi.nlm.nih.gov/pubmed/16108820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02201.x
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