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Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males

Adrenomedullin (AM) is a potent vasodilator peptide in plasma at picomolar levels. Polymorphisms in the human AM gene have been associated with genetic predisposition to diabetic nephropathy and proteinuria with essential hypertension, and numerous studies have demonstrated that endogenous AM plays...

詳細記述

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書誌詳細
主要な著者: Caron, Kathleen, Hagaman, John, Nishikimi, Toshio, Kim, Hyung-Suk, Smithies, Oliver
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802008/
https://ncbi.nlm.nih.gov/pubmed/17360661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611365104
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