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Relationship between rat renal accumulation of gentamicin, tobramycin, and netilmicin and their nephrotoxicities.

Gentamicin, tobramycin, and netilmicin were given to rats in daily doses of either 5 or 20 mg/kg for 30 days to determine the renal accumulation kinetics of the compounds and to correlate steady-state renal parenchymal concentrations with nephrotoxicity. Four rats from each group were sacrificed dai...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Brier, M E, Mayer, P R, Brier, R A, Visscher, D, Luft, F C, Aronoff, G R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4015072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.5.812
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