Relationship between rat renal accumulation of gentamicin, tobramycin, and netilmicin and their nephrotoxicities.

Gentamicin, tobramycin, and netilmicin were given to rats in daily doses of either 5 or 20 mg/kg for 30 days to determine the renal accumulation kinetics of the compounds and to correlate steady-state renal parenchymal concentrations with nephrotoxicity. Four rats from each group were sacrificed dai...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Brier, M E, Mayer, P R, Brier, R A, Visscher, D, Luft, F C, Aronoff, G R
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1985
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180157/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4015072/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.5.812
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