Analysis of amifloxacin in plasma and urine by high-pressure liquid chromatography and intravenous pharmacokinetics in rhesus monkeys.

An analytical method for the quantitation of amifloxacin, 6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3- quinolinecarboxylic acid, in plasma and urine has been developed. The method involves extraction with chloroform, back-extraction into 0.1 M sodium hydroxide, and subseq...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	McCoy, L F, Crawmer, B P, Benziger, D P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180150/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4015070/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.5.769
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