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Loss of heterozygosity in chondrosarcomas for markers linked to hereditary multiple exostoses loci on chromosomes 8 and 11.

Hereditary multiple exostoses (EXT; MIM 133700) is an autosomal dominant condition characterized by growth of multiple benign cartilage-capped tumors. EXT greatly increases the relative risk to develop chondrosarcoma, although most chondrosarcomas are sporadic. This observation suggests that, like t...

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Bibliografiska uppgifter
Huvudupphovsmän: Raskind, W H, Conrad, E U, Chansky, H, Matsushita, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801462/
https://ncbi.nlm.nih.gov/pubmed/7726169
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