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Deletions of the elastin gene at 7q11.23 occur in approximately 90% of patients with Williams syndrome.

To investigate the frequency of deletions of the elastin gene in patients with Williams syndrome (WS), we screened 44 patients by both FISH and PCR amplification of a dinucleotide repeat polymorphism. FISH was performed using cosmids containing either the 5' or the 3' end of the elastin ge...

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Detalles Bibliográficos
Main Authors: Nickerson, E, Greenberg, F, Keating, M T, McCaskill, C, Shaffer, L G
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801441/
https://ncbi.nlm.nih.gov/pubmed/7726172
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