Biotransformation and elimination of [2-14C]-1-(2-deoxy-2'-fluoro-beta-D -arabinofuranosyl)-5-iodocytosine in immunosuppressed patients with herpesvirus infections.

The metabolism of the drug [2-14C]-1-(2'-deoxy-2'-fluoro-beta-D -arabinofuranosyl)-5-iodocytosine (FIAC), a potent inhibitor of herpesvirus replication, was studied in immunosuppressed patients with herpesvirus infections. FIAC was administered intravenously by 15-min infusion and by mouth 24 h late...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Feinberg, A, Leyland-Jones, B, Fanucchi, M P, Hancock, C, Fox, J J, Watanabe, K A, Vidal, P M, Williams, L, Young, C W, Philips, F S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1985
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180143/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2990323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.5.733
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