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Therapeutic activities of 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-iodocytosine and -thymine alone and in combination with acyclovir and vidarabine in mice infected intracerebrally with herpes simplex virus.

The therapeutic effectiveness of two new antiviral agents, 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-iodocytosine and 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)thymine, was compared with that of acyclovir and vidarabine. In mice inoculated intracerebrally with high 50% lethal doses of herpes...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Schinazi, R F, Peters, J, Sokol, M K, Nahmias, A J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185110/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6625559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.1.95
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