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Therapeutic activities of 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-iodocytosine and -thymine alone and in combination with acyclovir and vidarabine in mice infected intracerebrally with herpes simplex virus.

The therapeutic effectiveness of two new antiviral agents, 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-iodocytosine and 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)thymine, was compared with that of acyclovir and vidarabine. In mice inoculated intracerebrally with high 50% lethal doses of herpes...

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Main Authors: Schinazi, R F, Peters, J, Sokol, M K, Nahmias, A J
格式: Artigo
語言:Inglês
出版: 1983
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC185110/
https://ncbi.nlm.nih.gov/pubmed/6625559
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