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Multiple mutations are responsible for the high frequency of metachromatic leukodystrophy in a small geographic area.
Metachromatic leukodystrophy is a lysosomal storage disorder caused by the deficiency of arylsulfatase A. The disease occurs panethnically, with an estimated frequency of 1/40,000. Metachromatic leukodystrophy was found to be more frequent among Arabs living in two restricted areas in Israel. Ten fa...
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主要な著者: | , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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1995
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1801341/ https://ncbi.nlm.nih.gov/pubmed/7825603 |
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