De novo amyloid proteins from designed combinatorial libraries

Amyloid deposits are associated with several neurodegenerative diseases, including Alzheimer’s disease and the prion diseases. The amyloid fibrils isolated from these different diseases share similar structural features. However, the protein sequences that assemble into these fibrils differ substant...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	West, Michael W., Wang, Weixun, Patterson, Jennifer, Mancias, Joseph D., Beasley, James R., Hecht, Michael H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11211
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