Detection of eight BRCA1 mutations in 10 breast/ovarian cancer families, including 1 family with male breast cancer.

Genetic epidemiological evidence suggests that mutations in BRCA1 may be responsible for approximately one half of early onset familial breast cancer and the majority of familial breast/ovarian cancer. The recent cloning of BRCA1 allows for the direct detection of mutations, but the feasibility of p...

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Detalhes bibliográficos
Main Authors: Struewing, J P, Brody, L C, Erdos, M R, Kase, R G, Giambarresi, T R, Smith, S A, Collins, F S, Tucker, M A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801253/
https://ncbi.nlm.nih.gov/pubmed/7611277
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