Yüklüyor......
The molecular basis of HEXA mRNA deficiency caused by the most common Tay-Sachs disease mutation.
Tay-Sachs disease (TSD) is a catastrophic neurodegenerative disorder caused by mutations in the HEXA gene. The most common TSD allele worldwide contains a 4-bp insertion in exon 11 that produces a downstream premature termination codon. Despite normal transcription of this allele, HEXA mRNA is sever...
Kaydedildi:
| Asıl Yazarlar: | , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
1995
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1801160/ https://ncbi.nlm.nih.gov/pubmed/7887427 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|