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Expression of a non–DNA-binding isoform of Helios induces T-cell lymphoma in mice

Helios is a zinc-finger protein belonging to the Ikaros family of transcriptional regulators. It is expressed, along with Ikaros, throughout early stages of thymocyte development where it quantitatively associates with Ikaros through C-terminal zinc-finger domains that mediate heterodimerization bet...

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Detalhes bibliográficos
Main Authors: Zhang, Zheng, Swindle, C. Scott, Bates, John T., Ko, Rose, Cotta, Claudiu V., Klug, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801072/
https://ncbi.nlm.nih.gov/pubmed/17110463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-031930
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