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Inositol polyphosphate derivative inhibits Na(+) transport and improves fluid dynamics in cystic fibrosis airway epithelia
Amiloride-sensitive, epithelial Na(+) channel (ENaC)-mediated, active absorption of Na(+) is elevated in the airway epithelium of cystic fibrosis (CF) patients, resulting in excess fluid removal from the airway lumen. This excess fluid/volume absorption corresponds to CF transmembrane regulator-link...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800890/ https://ncbi.nlm.nih.gov/pubmed/15857902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00591.2004 |
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