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Reduced Folate Supply as a Key to Enhanced l-Serine Production by Corynebacterium glutamicum
The amino acid l-serine is required for pharmaceutical purposes, and the availability of a sugar-based microbial process for its production is desirable. However, a number of intracellular utilization routes prevent overproduction of l-serine, with the essential serine hydroxymethyltransferase (SHMT...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800755/ https://ncbi.nlm.nih.gov/pubmed/17142381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02208-06 |
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