Characterization of Saccharomyces cerevisiae Npa2p (Urb2p) Reveals a Low-Molecular-Mass Complex Containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p Involved in Early Steps of 60S Ribosomal Subunit Biogenesis

We report the characterization of the yeast Npa2p (Urb2p) protein, which is essential for 60S ribosomal subunit biogenesis. We identified this protein in a synthetic lethal screening with the rsa3 null allele. Rsa3p is a genetic partner of the putative RNA helicase Dbp6p. Mutation or depletion of Np...

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Detalhes bibliográficos
Main Authors: Rosado, Iván V., Dez, Christophe, Lebaron, Simon, Caizergues-Ferrer, Michèle, Henry, Yves, de la Cruz, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800719/
https://ncbi.nlm.nih.gov/pubmed/17145778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01523-06
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